AI & Robotics in Neurocritical Care & Neurosurgery

Brought to you by The Artificial Intelligence Group, The Healthcare Group

A joint event between CW and the NIHR Brain Injury MedTech Co-operative bringing together leaders in healthcare, academia and industry to exchange ideas in the field of artificial intelligence and robotics as applied to neurocritical care, neuroradiology and neurosurgery.

About the event

The third NIHR Brain Injury MedTech Co-operative BITT tank will focus on the development of Artificial Intelligence in neurointensive care.

The revolution in artificial intelligence (AI) is impacting every aspect of our lives, none more so than in healthcare. The value of AI is in its ability to make sense of large amounts of data in a short amount of time. It is also ideally suited to integrate data and is not susceptible to the biases, assumptions and omissions common in human decision making.

Neurointensive care is a challenging specialty in that sick patients are often admitted with multiple serious problems, rapid diagnosis is essential, early warning of impending deterioration crucial and accurate prognostication important. Neurointensive care is data rich, but rarely integrated. There is a tendency in the management of the critically ill patient to treat data as discrete, linear and stationary and the inherent complexity within the whole patient often overlooked. However, almost by definition the critically ill patient with multi-organ failure has ‘whole-system’ failure. Even if the clinician appreciates these complexities, the sheer volume of data makes it impossible for adequate interpretation of what that data is showing accurately in real time.

The challenge of bringing AI into the critical care unit is not straightforward; not least because of the variety and magnitude of data and complexity of integrating the data. Different AI methodologies exist and would need to be validated in different clinical situations and populations. While individual patients are ‘data rich’, AI cannot draw on large population data and the infrastructure within the NHS is not yet robust enough to compile data from critical care units nationwide. Nevertheless, the technology is developing rapidly, the need is urgent and benefits immense.

The purpose of this BITT tank is to bring together expertise in neurocritical care medicine (adult, paediatric and neonatal) with developers, scientists and engineers in the field of AI to explore challenges, collaborations and possible solutions in the acute monitoring and management of brain injury.


The Technology Showcase: 4 x 15min presentations (with Q&A). Allocated on first-come first-served basis.

Please, contact Francesca Piffer if you're interest in presenting


You can follow @CambWireless on Twitter.

In collaboration with NIHR Brain Injury MedTech Co-operative

The NIHR Brain Injury MedTech Co-operative provides a “go-to” centre of expertise for understanding the Acquired or Traumatic Brain injury care pathway.

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Agenda

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The information supplied below may be subject to change before the event.

09:30

Registration & Networking over Tea and Coffee

10:00

Welcome and Opening Remarks

10:05

CW Intro by Peter Whale

10:10

Session 1: ARTIFICIAL INTELLIGENCE AND ROBOTICS IN CLINICAL SETTINGS

Chaired by Professor Topun Austin, Deputy Director, NIHR Brain Injury MedTech Co-operative

10:10

Opportunities and unmet needs for AI in Neonatal Care: Prof. Topun Austin; NIHR

10:30

Opportunities and unmet needs for AI in Intensive Care; Ari Ercole

10:45

Opportunities and unmet needs for AI in Neurosurgery (and Robotics?) ; Hani Marcus, UCL

11:00

Ai in Neuroimaging; Dr Emmanuel Stamatakis, University of Cambridge

11:15

Refreshments and networking

11:30

Future Commissioning and New Technologies; Richard Kerr, Oxford University NHS Trust

12:00

Session 2: TECHNOLOGY SHOWCASE (part 1)

Chaired by Peter Ferguson, Director for Healthcare Technologies, Arm & CW Healthcare SIG Champion

12:00

AI SIG Intro and Scene Set: Peter Whale, Vision Formers & Phil Claridge ; Mandrel Systems

12:15

SME Experience; Antony Rix, Granta Innovation

12:30

Paul Winter, TTP

12:45

Paul Brennan

12:45

Dr Virginia Newcombe

13:00

Lunch, Networking & Technology Exhibition

14:00

Directed Systems – Mark S Leaning

14:00

Session 2: TECHNOLOGY SHOWCASE (part 2)

Chaired by Dr Peter Jarritt, Deputy Director, NIHR Brain Injury MedTech Co-operative & CW Healthcare SIG Champion

14:15

Peter Smielewski

14:30

Speaker to be confirmed

14:45

Speaker to be confirmed

15:00

Tea Break

15:15

Session 3: HORIZON SCANNING

Chaired by Richard Kerr

15:15

Ethics and AI

15:30

Legal & Regulatory Landscape AI in Healthcare – Claudia Martinez, Reform

15:45

Panel discussion

 Claudia Martinez, Reform
 Dr Ian Newington, NIHR
 EAHSN
 Peter Whale, Vision Formers & AI SIG Champion

16:00

Networking & refershements

16:30

Event Closes

Speakers

Topun Austin - Deputy Director, NIHR Brain Injury MedTech Co-operative

Prof. Topun Austin is Consultant Neonatologist in Cambridge and Honorary Professor of Neurophotonics at University College London and has an interest in brain injury and imaging in the newborn. He leads the Evelyn Perinatal Imaging Centre (EPIC), based at the Rosie Hospital, Cambridge. The centre has a dedicated infant functional brain imaging unit and also houses a 1.5T MRI scanner for mothers and babies. The research interests of the group are in the development of monitoring and imaging technologies to identify vulnerable infants at an early stage. He is also founder of neoLAB, a formal collaborative group between EPIC and Biomedical Optics Laboratory at UCL. The group has been involved in developing an integrated optical-EEG system to study neurovascular coupling as well as a unique fast optical tomography system for 3D imaging of regional blood flow and oxygenation. Prof. Austin is also involved in the development of the NeuroNICU at the Rosie Hospital, in collaboration with Prof. David Rowitch.

He is a collaborator on a number of cognitive developmental psychology studies, including the invesitigation of brain function and development in children in high and low-income settings, imaging the brain of infants at high risk of developing autism and investigating neurophysiological and genetic biomarkers of dyslexia in newborn infants.

He has given a number of public lectures and media appearances, including the BBC One documentary ‘Born Pre’, describing the challenges faced by premature babies, ‘The Golden Window, a film made in collaboration with BAFTA award-winning film producer Dr. Shreepali Patel, giving an infants perspective of the neonatal intensive care unit. He regularly speaks at the Cambridge Science Festival and in 2016 was invited to speak at the Hay Festival.

Paul Brennan - Senior Clinical Lecturer in Neurosurgery, University of Edinburgh

Paul is Senior Clinical Lecturer and Honorary Consultant Neurosurgeon at the University of Edinburgh and NHS Lothian. He combines his operative work with laboratory research into the origin of gliomas. He also has an active involvement in clinical research and was co-founder of the British Neurosurgical Trainee Research Collaborative that he helped found as Chair of the British Neurosurgical Trainees Association in 2012. 

Complementing his clinical work, Paul founded eoSurgical Ltd in 2012 along with co-founders Roland Partridge and Mark Hughes. The University spin-out now provides surgical simulation training around the world.  

In 2014 Paul helped in the foundation of the Compassion Initiative at the University of Edinburgh and is a co-Director, working in close collaboration with Prof Jim Doty's Centre for Compassion and Altruism Research at the University of Stanford.

Paul is a member and co-chair of the Young Academy of Scotland.

Ari Ercole - Joint Director of Studies in Medical Sciences, College Lecturer in Clinical Medicine, University of Cambridge

Dr Ari Ercole is a Fellow in Clinical Medicine at Magdalene. Dr Ercole directs studies for Part II of the Medical tripos and he is an Honorary Senior Research Associate in the Division of Anaesthesia.

In addition to his role at Magdalene, Dr Ercole is a consultant in neurosciences and trauma intensive care at Cambridge University Hospitals NHS Foundation Trust (CUHFT). His clinical interests focus on the physiological measurement, support and resuscitation of critically ill patients, in particular patients that have sustained life threatening severe trauma.

Prior to his medical training, he completed a degree and PhD in condensed matter physics from the University of Cambridge.

Richard Kerr - Consultant Neurosurgeon, Oxford University Hospitals NHS Trust

Hani Marcus - Consultant Neurosurgeon, University College London

Mr Marcus is an academic consultant neurosurgeon, and was among the first cohort of trainees to be selected for a Walport Integrated Academic Training Pathway, with rotations at the University of Cambridge, Imperial College London, and University College London.

His clinical interest is in “keyhole” endoscopic neurosurgical approaches. To this end, he completed fellowships in endoscopy and anterior skull base surgery (including pituitary surgery) at the Klinik Hirslanden, Zurich and the National Hospital for Neurology and Neurosurgery. His research interest, and the subject of his doctoral thesis under Prof Lord Darzi, is the development and evaluation of new devices that makes these keyhole approaches more safe and effective, including augmented reality, robotics, and artificial intelligence. 

His work has received over £1.5 million in research funding, has resulted in over 75 peer-reviewed publications, and has frequently featured in the national press. In recognition of these achievements he was commissioned by Springer to act as Editor on their first book dedicated to Neurosurgical Robotics, serves as a Member of the Advisory Group on Robotic Surgery in the United Kingdom, and has been awarded several prizes, including the prestigious Hunterian Professorship by the Royal College of Surgeons of England in 2019.

Claudia Martinez - Research Manager, Reform

I joined Reform as Research Manager in November 2018 with an interest in digital innovation, health tech and social care policy. Prior to joining Reform I was a Senior Analyst at the Research & Innovation Department at Centra - the technology and care & support arm of Clarion Housing Group. In this role I focused on delivering Centra’s innovation programme, leading on the evaluation and integration of cutting-edge assistive technologies. I was also involved in strategic research projects, including assessing the impact of the digital switchover on housing providers, and evaluating the effect of AI-powered monitoring technologies on people’s health and wellbeing outcomes. I am passionate about “technology for good’’ and its potential to deliver transformative change in public service delivery.

I also worked as a management consultant in the mining and metals industry in Chile and as a researcher at a London-based social impact agency. I have an undergraduate degree in Economics from the University of Chile and MSc in Politics and Globalisation from King’s College London.

In my spare time I like to travel, practise yoga, and go to the theatre. I also volunteer at a community garden in East London a couple of weekends a month.

Virginia Newcombe - Clinician Scientist, University of Cambridge

Ian Newington - Head of Special Projects, NIHR Brain Injury MedTech Co-operative

Having led the i4i Programme Team until July, Ian now heads up Special Projects and medtech
SME engagement in the CCF Innovations team. He also manages a portfolio of funded projects
across i4i and Health Innovation Challenge Fund (HICF) and the contract for the NIHR
Innovation Observatory. Prior to this, a DPhil (Oxon) in chemistry led to Ian joining Kodak Ltd,
becoming a Principal Scientist in the European R&D labs, followed by 9 years at GE Healthcare
Life Sciences, Imaging R&D, leading the Discovery portfolio for molecular imaging in
neurodegenerative disease. Ian is a (co-)inventor on 38 patent applications.

Antony Rix - CEO & Founder, Granta Innovation

Antony Rix gained his PhD developing PESQ, a patented AI model of the human auditory system applied to predict the quality of phone calls. This formed the basis of his first startup, Psytechnics, which was acquired by Netscout in 2011. He spent 12 years working at TTP on innovative connected digital systems, software and medical devices, before founding industrial IoT startup 8power in 2016. Antony is a member of the IET and American Telemedicine Association. Antony set up Granta Innovation in early 2018 and focuses on developing and gaining clinical acceptance of tools to transform the diagnosis of cancer using AI and magnetic resonance imaging.

Peter Smielewski - Senior Research Associate; Systems and Computational Neuroscience, University of Cambridge

In an established environment of Clinical Neuroscience Dept large quantities of data can be captured from bed-side monitors. Using that data, continuous assessment of changing cerebrovascular haemodynamics and oxygenation is possible but requires sophisticated signal analysis. My primary research involves development of ICM+ software which encapsulates 20 years of our experience in brain monitoring gained in multiple neurosurgical and intensive care centres. It collects data from bedside monitors and produces on-line trends of parameters defined using highly configurable signal processing formulae. Using a variety of statistical charts complex information coming off the bedside monitors can be summarized in a concise fashion and presented to medical staff in a simple way that alerts them to the development of various pathological processes. The software is now installed in a number of academic centres around the world providing basis for multi-centre collaborations in brain monitoring.

https://www.neurosurg.cam.ac.uk/

Emmanuel Stamatakis - Lead, Cognition and Consciousness Imaging Group, University of Cambridge

Dr. Emmanuel A Stamatakis has been working in the field of cognitive/clinical neuroimaging since the completion of his PhD (Computer Science). He leads the Cognition and Consciousness Imaging Group in the Division of Anaesthesia, University of Cambridge. He uses neuroimaging tools such as fMRI and EEG and computational approaches to answer cognitive/clinical neuroscience questions by investigating functional relationships between remote brain regions which form networks. His research focus is the function of the default mode network and the significance of its interactions with attentional networks in health and disease. He is also interested in the pharmacological modulation of brain network interactions. His main objective is to improve the neuroscientific understanding and treatment of brain injury and coma. 

SIG Champions

Laurent Brisedoux - Senior Manager, Amazon

Laurent has been heading the Amazon R&D team in Cambridge, part of the Lab126 organization, since its creation in 2014. His group is responsible for developing software for Amazon’s consumer electronic devices such as Cloud Cam, Echo Look, Echo Show and many more innovative products to come. Prior to that, Laurent was in charge of the development and productisation of imaging technologies at Broadcom. He joined the Broadcom Mobile Multimedia group in 2004 with the acquisition of Alphamosaic, one of the Silicon Fen ’success stories’. Laurent is also a junior angel investor and working with several technology startups in the Cambridge area.

Phil Claridge - Founder, Mandrel Systems

Phil Claridge is a ‘virtual CTO’ for hire within Mandrel Systems covering end-to-end systems. Currently having fun and helping others with large-scale AI systems integration, country-wide large scale big-data processing, hands-on IoT technology (from sensor hardware design, through LoRa integration to back end systems), and advanced city information modelling. Supporting companies with M&A ‘exit readiness’, due-diligence and on advisory boards. Past roles include: CTO, Chief Architect, Labs Director, and Technical Evangelist for Geneva/Convergys (telco), Arieso/Viavi (geolocation), and Madge (networking). Phil’s early career was in electronics, and still finds it irresistible to swap from Powerpoint to a soldering iron and a compiler to produce proof-of-concepts when required.

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Richard Dearden - Senior Director and Advanced Analytics Project Leader, AstraZeneca

Richard is a Senior Director in R&D Data Science and Artificial Intelligence at Astrazeneca in Cambridge, UK. He leads a team doing a wide variety of data analytics, artificial intelligence and optimisation projects in the areas of clinical trial design and clinical supply chain. Richard is also an industrial advisor for the University of Birmingham-based National Centre for Nuclear Robotics. He has spent six years in industry, previously working at Schlumberger’s Cambridge Research Centre where he led a robotics and AI team working on drilling automation and other oilfield applications.

Prior to joining Schlumberger, Richard was Reader in Intelligent Robotics at the University of Birmingham, where he was a principal investigator on a number of UK and European-funded research projects, including work on robotic manipulation with the German Space Agency, DLR, and on autonomous underwater vehicles with the National Oceanographic Centre. He has over 70 academic publications in the field of artificial intelligence, largely in the areas of automated planning under uncertainty, robotics, machine learning and fault diagnosis.

From 1999 until 2005 Richard worked as a research scientist at NASA Ames Research Centre, and for part of that time ran the Model-based Diagnosis and Recovery Group. He worked primarily on the Mars Exploration Programme, including work on planning daily activities and fault diagnosis for Mars rovers. His team also developed the Livingstone 2 fault diagnosis engine which was used for a number of project including being successfully deployed on-board the EO-1 satellite mission.

Richard studied Computer Science at Victoria University of Wellington, New Zealand and obtained his doctorate on Markov decision problems and reinforcement learning in structured worlds from the University of British Columbia, Canada.

Gunter Haberkorn - Senior Manager Product & Technology, Magna International

Gunter works in the Corporate R&D Department and has years of experience in complete vehicle engineering. He is looking into Product and Technology trends within the automotive industry with a special interest in autonomy, mobility solutions, manufacturing and electrification and especially technologies which can support advancements in these areas.

Vaiva Kalnikaite - Founder , Dovetailed

Vicky Schneider - Senior Scientific Programme Manager, Amazon

Currently Senior Scientific Program Manager at the Amazon Development Centre in Cambridge, UK. Vicky works in the Machine Learning Team and is involved in a variety of academic engagements around ML and AI, including outreach, education and training initiatives. Previously Deputy Director of EMBL Australian Bioinformatics Resource (www.embl-abr.org.au) and Associate Professor at the University of Melbourne. Vicky remains an Honorary Principal Fellow at the University of Melbourne and is an academic visitor at the University of Cambridge where she collaborated with the Bioinformatics Training Team.  Before Australia, Vicky was at the Earlham Institute (Norwich), as part of the Senior Management Team and Head of Training and Outreach which evolved to Head of Scientific Training, Education and Learning Division. In the previous years Vicky has been responsible for the strategic coordination and implementation of the EMBL-EBI’s User-Training programme which has pass now ten years and continues to provide training for the scientific users of the EMBL-EBI’s data services. Prior to joining the EMBL-EBI in 2007 Vicky held an Assistant Professor position at the University of Bern and the Institute for Aquatic Sciences (EAWAG) and postdocs at the University of Zurich and University of Rome (Torvergata). Vicky studied biology at the University of Rome and obtained her PhD on the evolution of sex at the University of Leiden (NL) and Lyon (France). Vicky has been extensively involved in the acquisition, management and implementation of funded research and training projects throughout her career.

Peter Whale - Founder, Vision Formers

Peter is founder of Vision Formers, a specialist consultancy that helps visionary technology businesses get product to market and turn their ideas into reality. Peter has a long track record of conceiving, developing and marketing successful technology-based solutions, deployed at scale, globally. Innovative products Peter has brought to market in digital, cloud, AI, consumer electronics and telecommunications have been used by countless millions of people on a daily basis globally, badged by the world’s leading digital and technology brands. Peter is a board member of CW (Cambridge Wireless), and co-leads its Artificial Intelligence special interest group.

Leila Ali - Founder, Digital Health Cambridge

Leila is passionate about applying innovative approaches in bridging the worlds between health and technology. She has worked in the health sector for over 10 years and understands the importance of identifying opportunities of engagement and the evolving needs of patients/clients. She has worked in Sweden, UK and Kenya and has been instrumental in implementing innovative health promotion initiatives and identifying potential avenues for improving user engagement. She has previously worked with product planning, putting the user at the centre of the design process and ensuring a holistic view is taken of the product experience.

She has the ability to horizon-scan, spot needs, and creatively reinterpret a broad strategy. Leila is also the founder and organiser of Digital Health Cambridge, a meet-up group that brings together various stakeholders, clinicians, investors and startups in Cambridge to foster a multi - stakeholder partnership. She is currently an eHospital support link at Cambridge University Hospitals NHS Foundation Trust, where she trains and supports colleagues regarding best practice using Epic (electronic patient record system). A digital strategy which enables clinicians to use the latest in computer technology to help them to consistently provide high quality patient care.

Peter Ferguson - Director for Healthcare Technologies , Arm

Peter is director for healthcare technologies at Arm and has been actively involved in the delivery of mobile and healthcare solutions since starting his Medical Electronics PhD in 1994. Based in Cambridge, UK, Peter is responsible for driving Arm's health strategies in Medical Sensors and Genomics. His remit is helping the healthcare industry to utilize Arm's high efficiency technology in developing new products and services. Peter has more than 20 years' experience working in the healthcare, mobile tech and pharmaceutical technology market and has been instrumental in delivering innovative mobile health solutions including wearable ECG, Mobile Devices, Adverse Event Systems and Portal Hospital solutions in the UK and China.

Peter Jarritt - Deputy Director, NIHR Brain Injury MedTech Co-operative

Peter is currently Deputy Director and technology theme lead for the National Institute for Health, Health Technology Cooperative for Brain Injury. He is an Honorary Fellow of the Royal College of Physicians as well as a Fellow of IPEM. He is also a member of the Advisory Board of the Centre for Healthcare Photonics at the Centre for Process Innovation. Peter has more than 20 years’ experience directing and delivering a comprehensive range of Medical Physics and Clinical Engineering services at the highest level. Most recently Peter was the Clinical Director and Head of Medical Physics and Clinical Engineering at Cambridge University Hospitals NHS Foundation Trust. Notable projects under his leadership were introduction of RFID technology at Addenbrookes to enhance utilization of medical devices in the patient environment and the integration of medical devices into clinical information systems in an e-hospital programme. Peter’s other Career highlights includes Chief Executive of Northern Ireland Regional Medical Physics Agency. He also served as President of the Institute of Physics and Engineering in Medicine (IPEM) promoting the use of Physics and Engineering for patient benefit at national and international level.

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Siddhi Trivedi - Founder, Beowulf Proof Works

With 30 years of Health & Education innovation Siddhi provides support and advice to start-ups and entrepreneurs globally.

With a background in Pharmacology, Business Management and Coaching, she enjoys mentoring, advising start-ups and young people to help them achieve their aspirations. She wants to foster collaborations and is a passionate connector and

actively involved in many networks including Cambridge Wireless, London Tech Advocates Blockchain Steering Group, and, as License holder for TEDxLeicester, a member of the global TEDx tribe of shapers and thinkers. Her experiences in health and education innovation have been gleaned within the NHS, Education, Consultancy and Pharmaceutical sectors; and has managed projects with budgets of up to £32M. Currently she is  focused on the application of AI and Blockchain technology for improving health and create social impact  As an experienced businesswoman in leadership, relationship management and effective project management, she believes success is based on building long-term sustainable partnerships and collaborations both at a local and global level. 

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Nigel Whittle - Head of Medical & Healthcare, Plextek

Nigel is Head of Medical & Healthcare at Plextek, spearheading engagement with a range of clients in the medical device sector, helping them develop innovative technology around sensors, data collection, communications and related areas. Nigel has over 25 years’ experience in the global life science industry, in a wide range of senior scientific, commercial and managerial roles. He conducted research work at Genentech and Celltech, then at Cantab Pharmaceuticals he was responsible for all company product development, taking proprietary products into late-stage Clinical Trials. With the IP Group he established a programme of technology commercialisation from Kings College London, including start up and flotation of companies. Later, working for UK Trade & Investment, Nigel worked with a portfolio of overseas pharmaceutical companies to secure high-level investment into the UK’s R&D capabilities. More recently he has worked as a business consultant both as an independent and at Sagentia. His current interests include the development of wearable technology to support clinical studies, and the use of monitoring systems for assisted living.

Paul Winter - Senior RF Consultant, TTP plc

Paul Winter is a programme manager and RF engineer in the Communications and Wireless group at TTP. He has led numerous projects in commercial, industrial and healthcare sectors developing connected devices and precision instrumentation. Paul has a heritage in developing products integrating multiple wireless standards including GPS, GPRS, Wi-Fi, Bluetooth and proprietary ISM band radios, deployed within multi-sensor systems for in-home and on-body applications, often coupled to 'Cloud' based analysis and visualisation services. In healthcare Paul has applied aspects of wireless, antennas and electronics to a number of medical devices including inhalers, glucose testing and point of care diagnostic instruments. Paul has also led several incubation projects for TTP's Carbon Trust Incubator, covering a wide range of cutting edge technologies. Paul joined TTP in 2006; prior to this he worked as a radio engineer for Global Communications developing high volume consumer in-home satellite and digital TV distribution equipment, as well as portable equipment for the 'on-location' broadcasting industry. Paul has a Masters degree in Electrical & Electronic Engineering from the University of Wales, Cardiff. He is a member of the Institute of Engineering and Technology, the Royal Academy of Engineering and is a Charted Engineer.

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Event Location

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Madingley Hall, Madingley, Cambridge, CB23 8AQ

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